Custom TruCytes® Biomarker Controls

Custom cell mimics, built to your spec.

Precision-engineered cell mimics designed to your exact specifications — for rare indications, novel targets, and complex multi-biomarker panels.

  • A free, no-obligation consultation
  • Direct access to a Field Application Scientist
See the case studies

Request a consultation

A Field Application Scientist replies within 2 business days — no sales pressure.

No obligation · Reply <2 business days · Talk to a scientist

100+ custom mimics completed
Proven success
<10% CV
Lot-to-lot consistency
Non-biohazardous
Safe synthetic materials

Trusted by the world's leading pharma, biotech, and CROs

Bristol Myers Squibb
Novartis
Gilead
Johnson & Johnson
Takeda
Pfizer
Roche
Amgen
Regeneron
Merck
BD
Beckman Coulter
Charles River
Resilience
Lonza
NeoGenomics
Process overview

Designing and building your Custom TruCytes®

Our commercial and R&D teams work alongside your scientists under a structured project-management framework — delivering your Custom TruCyte on time, on budget, and to a defined quality standard.

With more than 100 custom mimic designs completed, our process is proven. Expect maximum efficiency through design and build, and optimal quality at delivery.

100+ custom mimic designs completed
  1. 01

    Evaluation

    Begin with a no-cost consultation with our Business Development Executive and Field Application Scientists to define the specifications, functionality, and performance targets for your ideal TruCyte.

  2. 02

    Feasibility & customization

    Our R&D team assesses feasibility and maps decision-gating milestones, with a complete risk assessment, cost estimate, and development timeline.

  3. 03

    Scale-up & validation

    Rigorous verification and validation establish the foundation for adoption. Dedicated Field Application support ensures a smooth, confident transition to large-scale production.

  4. 04

    Production

    Production scales as your needs grow. Lot sizes adjust to demand, replenishment is scheduled in advance, and ongoing training and on-site support remain available.

Product capabilities

Configure a control that matches your assay exactly

Custom TruCytes® deliver consistency, accuracy, and scalability tailored to your specific research workflow. Each control can be configured across a range of parameters.

  • Surface biomarkers

    Configure single or multiple surface biomarkers for precise antigen detection and quantification.

  • Tailored antigen levels

    Highly stable, reproducible signal detection at intensities previously out of reach with biological samples.

  • Viability compatibility

    Integrate seamlessly with DNA- and amine-based viability reagents used in standard laboratory protocols.

Custom TruCyte biomarker configuration diagram
What you can configure

Unparalleled customization across therapeutic areas

Our patented technology mimics specific cellular expression levels for advanced research, diagnostic, and therapeutic applications — down to the individual biomarker.

CD138CD34CD4CD8CD20CCR7Custom CAR+200 more
01

Single or multiple proteins

Incorporate one or more rare or targeted biomarkers on a single TruCyte to replicate complex cellular populations.

02

Distinct populations

Model heterogeneous cell environments by defining distinct populations within a sample.

03

Variable expression levels

Fine-tune biomarker expression to reflect high, low, or intermediate intensities for more accurate assay development.

04

Surface & intracellular biomarkers

Create controls for both surface and intracellular biomarkers to solve challenges for your whole panels.

05

Rare or novel proteins

Access non-commercial proteins through our expertise in isolation and incorporation — even the most niche targets.

06

Size & morphology control

Select TruCyte dimensions and morphology to match specific cell types by flow cytometry — lymphocytes, monocytes, granulocytes, and more.

Comparative reproducibility study

Cell mimics prove superior to biologic controls

In a global, multi-site instrument standardization study across 30+ flow cytometers, synthetic mimics eliminated the variability that donor-derived controls introduce.

Biological controls

Donor PBMCs create inherent data-quality challenges that compromise assay reliability.

Synthetic cell mimics

Synthetic reproducibility enables confident data interpretation and rapid issue detection.

Up to 60% variability

in population counts across sites, instruments, and operators.

Consistent detection

of all cell types across sites, machines, and operators.

Missed low-frequency cells

due to noise floor masking rare populations.

Tech errors immediately visible

as peaks stand out against a stable baseline.

Tech errors hidden in noise

making troubleshooting and QC nearly impossible.

Operator error detection

enables targeted training and site-integration QC.

Global, multi-site instrument standardization studyStandardized antibody panel and staining protocolOver 30 flow cytometers across multiple laboratories
Proven in partnership
In our search for reliable controls for cell therapy assays, partnering with Slingshot has been a game-changer. Together, we addressed significant challenges by engineering custom CD3 T-cell mimics.
Amina Kariminia

Amina Kariminia

Ph.D. · Immunologist, Analytical Development Scientist

…these off-the-shelf controls seamlessly slot into our processes. This enhances our workflow efficiency without having to compromise on data quality and reliability.
Dr. Veronica Nash

Dr. Veronica Nash

Cerba Research

Build your custom mimic

Build your own customized TruCytes®

A Field Application Scientist will reply within 2 business days to discuss a Custom TruCytes® solution matched to your application. No sales pressure — just science.

  • A free, no-obligation consultation
  • Direct access to a Field Application Scientist

Request a consultation

A Field Application Scientist replies within 2 business days — no sales pressure.

Reply <2 business days · No commitment