Standardize cytometry assays across instruments, operators, and sites. Reduce bridging studies, accelerate validation, and scale with confidence, without the variability of donor PBMCs, the safety burden of biohazardous materials, or the maintenance overhead of cell lines.
For teams running cytometry assays across instruments, operators, and sites, Slingshot provides cell-mimic controls that deliver biology-like behavior without donor PBMCs’ variability, biohazardous materials’ safety burden, or cell lines’ maintenance overhead, helping you standardize workflows, tighten assay performance, and reduce bridging studies.
Stable, scalable controls reduce dependence on donor materials that require repeated characterization. Stop re-proving your assay every time antibody lots or reagents change.
Precisely engineer controls for rare markers, novel endpoints, and cell therapy transgenes. From Ki-67 to CAR-T enumeration, we build mimics when commercial controls don’t exist.
Build the evidence regulators and QA expect. Our controls enable sensitivity, linearity, and LOD/LOQ assessment with documented precision and cross-platform performance.
Get controls when you need them, at any scale. Shelf life starting at ~12 months with lot-to-lot consistency that outperforms donor-derived materials.
Standardize biomarker assays and immune monitoring from translational research through pivotal trials. Reduce operator variability, support consistent spectral unmixing, and enable assay transfers between research and GLP/GCP environments.
Validate potency, identity, and purity endpoints with custom controls for CAR-T enumeration, transgene expression, and viral vector characterization. Replace donor PBMCs with stable mimics that support IND packages, process validation, and comparability studies.
Validate rare population detection and immunophenotyping workflows with controls engineered for markers where commercial options don’t exist. Enable linearity, LOD/LOQ, and precision studies without biohazardous donor materials or cell line maintenance.
Standardize release testing and in-process controls across client programs without maintaining donor banks. Scalable controls with extended shelf life reduce tech transfer timelines and support consistent QC strategies as you onboard new programs.
Eliminate client-to-client variability in immune monitoring and biomarker validation across multi-site programs. Stable controls enable faster method validation, reduce failed runs, and minimize bridging when transitioning assays between sites or reagent lots.
Slingshot Bio teamed up with Cerba Research to develop cell mimics for Ki-67, a protein vital to cancer research. The solution allowed Cerba to validate assays with greater accuracy and less variability than what was possible with live cells, improving consistency in results.
“Slingshot Biosciences can generate controls that truly mimic biological expression. It’s a game changer for our project … These cell mimics have the potential to fill gaps in rare marker controls needed for assay validation.”
Dr. Veronica Nash | US Regional Head of Flow Cytometry
Cerba Research
See how we helped Prolocor design the ideal control for their platelet FcγRIIa precision diagnostic test that quantifies FcγRIIa on the surface of platelets to guide clinical decision making.
“Clinicians need better tools to guide decision making on the choice of antiplatelet therapy in coronary artery disease patients, particularly after coronary stenting. The Prolocor pFCG® test will be an important asset as we tailor antiplatelet therapies to balance thrombotic and bleeding risk.”
Dominick J. Angiolillo, MD, PhD, FACC, FESC, FSCAI | Professor of Medicine, Chief, Division of Cardiology, Director, Thrombosis Research Center
University of Florida, College of Medicine-Jacksonville.
See how we partnered with Fred Hutch CPF QC to engineer custom CD3 T cell mimics with varying percentages of expression of the common CAR transduction marker epidermal growth factor receptor (EGFR) to validate their CAR T cell flow cytometry assays.
“In our search for reliable controls for cell therapy assays, partnering with Slingshot has been a game-changer. Together, we addressed significant challenges by engineering custom CD3 T-cell mimics.”
Amina Kariminia, Ph.D. | Immunologist, Analytical Development Scientist
Fred Hutch Cancer Center
Take your research to the next level with controls engineered for multi-site harmonization and validation-grade performance. Talk to one of our cell-based assay experts today about bringing cell mimics to your lab.
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