Every day, new ideas and innovations bring us closer to breakthroughs in how we diagnose, treat, and potentially cure diseases. Reproducibility, or the ability to replicate a scientific study and get results consistent with previous findings, is fundamental to advancing scientific research. Without reproducibility, scientists can’t verify conclusions, detect errors, or build on what’s already […]

As the cell therapy landscape evolves, regulatory oversight is becoming more stringent. FDA regulation 21 CFR Part 1271 urges cell therapy manufacturers to address challenges like sterility, reproducibility of product lots, and control of impurities during the production process. The FDA also mandates potency and viability testing, ensuring that each product batch meets robust quality standards. […]

Cell health is a critical parameter at multiple stages of the cell therapy process, ensuring that the cellular product is safe, functional, and of the highest therapeutic quality. The health of cells used in therapy is not just a metric; it’s a cornerstone of the therapy’s potential success. Ensuring that cells are healthy, functional, and safe benefits […]

Why am I seeing errors in my flow data? Flow cytometry is a versatile technology with varied applications throughout cell therapy, pharmaceutical, academic, and clinical institutions. While there are many different ways you can use this technology, the basic principles of panel design, compensation or spectral unmixing, and experimental controls remain the same. However, if […]

Instrument standardization can be an added burden to the already complicated flow cytometry workflow. Many products on the market can help address some of these pain points. However, these still come with their caveats, one of which is the inability to mimic the optical performance of white blood cell populations. This then requires adjustments of […]

As a young girl growing up in Kingston, Jamaica, Annalise and her younger brother would accompany their mother to scientific presentations, local conferences, and exhibitions put on by the Scientific Research Council, Jamaica’s principal public sector agency responsible for the fostering and coordination of scientific research, and the promotion of its application. As an executive […]

Fluorescent proteins such as enhanced green fluorescent protein (eGFP) and monomeric Cherry fluorescent protein (mCherry) are used in a wide range of flow cytometry-based applications such as cell sorting, marker expression analysis, functional studies with reporter systems, as well as cell viability and apoptosis assays. As such, they have become integral tools in answering complex […]

Even viability dyes need controls. Don’t have time to “kill” a control for this? Don’t worry- we have your back. Dead cells in flow cytometry add errors to data because they can bind nonspecifically to many reagents. This non-specific binding gives rise to false positive results in flow cytometry. Therefore, identifying and removing data points […]

If you work in cell biology or the immunology field, chances are that you’re familiar with flow cytometry. This technique measures and analyzes biological cells by suspending them in a stream of fluid and passing them through a laser beam. To get accurate results from flow cytometry, it’s important to use controls for compensation on […]

Are you a cell biologist, immunologist, or flow cytometrist? If so, you know how challenging it is to find quality control (QC) samples for your biomarker assays. This challenge is only heightened when working with rare diseases or rare biomarkers. Finding QC samples is not only time-consuming and incredibly costly but is also sometimes impossible. […]

Are you a scientist looking for an edge in your experiments? Introducing biomarker controls engineered from cell mimics to your workflow may be the answer. These novel controls are designed to go beyond the known limitations of blood, PBMCs, or cell lines and provide scientists with a robust and reliable control for a more accurate […]