TruCytes™ Biomarkers

Whether you need a single protein, multiple distinct populations, or complex phenotypic and functional biomarkers, we deliver unparalleled quality and performance to help you accelerate your research.

Our customizable technology provides unparalleled reliability for assays, enabling breakthroughs across various therapy areas.

At Slingshot Biosciences, we empower researchers and clinicians with precision-engineered TruCytes™ biomarker cell mimics designed to replicate specific cellular phenotypes and functions for advanced research, diagnostic, and therapeutic applications.

Single or Multiple Proteins

Incorporate one or multiple biomarkers on a single TruCyte to replicate complex cellular phenotypes.

Distinct Populations

Generate multiple TruCyte populations within a single sample to model heterogeneous cell environments.

Variable Expression Levels

Fine-tune biomarker expression levels to reflect high, low, or intermediate intensities for more accurate assay development.

Dynamic Surface or Intracellular Biomarkers

Include both surface and intracellular markers to mimic dynamic cellular functions or pathways.

Rare or Novel Proteins

Utilize our expertise in isolating and incorporating non-commercial proteins, ensuring even niche biomarkers are accessible.

lymphocytes

Size and Morphology Control

Tailor the size and structure of your TruCytes to match specific cell types, including lymphocytes, monocytes, or tumor cells.

Below is a list of commonly requested biomarkers. However, this is just the starting point—we can work with nearly any commercially available protein and isolate non-commercial proteins to create truly singular TruCytes.

BiomarkersTherapy Areas
CD3, CD4, CD8Immuno-oncology, T-cell therapies, autoimmune diseases
CD14, CD16Monocyte and macrophage biology, inflammation, sepsis, autoimmune diseases
CD19, CD20B-cell malignancies, CAR-T therapies, lymphoma, leukemia
CD25, CD127Regulatory T-cell biology, autoimmune diseases, cancer
CD27, CD30Hodgkin's lymphoma, non-Hodgkin's lymphoma, CAR-T therapies
CD33, CD34Hematopoietic stem cell transplantation, myeloid leukemia
CD38Multiple myeloma, chronic lymphocytic leukemia
CD45Immunophenotyping, leukemias, lymphomas
CD56, CD16Natural killer (NK) cell therapies, immuno-oncology
CD117Stem cell biology, mast cell disorders
CD134 (OX40), CD137Immuno-oncology, T-cell activation, cancer therapies
CD138Multiple myeloma
CD152 (CTLA-4)Immune checkpoint inhibitor therapies, cancer immunotherapy
CD154 (CD40L)T-cell activation, immune modulation
CD269 (BCMA)Multiple myeloma, CAR-T therapies
CD279 (PD-1), CD274 (PD-L1)Immune checkpoint blockade therapies, cancer immunotherapy
EGFR, TIM-3Solid tumors, targeted cancer therapies, immuno-oncology
CD2, CD5, CD7T-cell malignancies, immunophenotyping
CD22, CD24B-cell biology, autoimmune diseases, cancer
CD40, CD40L (CD154)Immune modulation, cancer, autoimmune diseases
CD52Chronic lymphocytic leukemia, multiple sclerosis
CD64, CD66Neutrophil biology, inflammation, infection
CD70Cancer immunotherapy, Hodgkin’s lymphoma
CD71Iron metabolism, anemia, cancer
CD84, CD86Antigen presentation, immune modulation
CD93Vascular biology, inflammation
CD112, CD155TIGIT pathways, cancer immunotherapy
CD114, CD115Growth factor receptor pathways, cancer, inflammation
CD120bTNF signaling, inflammation, autoimmune diseases
CD122, IL-2T-cell biology, cancer, autoimmune diseases
CD123Acute myeloid leukemia, hematologic malignancies
CD126, CD127Cytokine signaling, immune modulation
CD135Stem cell biology, leukemia therapies
CD137LT-cell activation, cancer immunotherapy
CD147Cancer, viral infections
CD203cAllergies, mast cell activation
CD213a1, CD213a2Asthma, allergic diseases
CD215Immune modulation, cancer
CD221Growth factor signaling, cancer
CD223 (LAG-3)Immune checkpoint blockade, cancer immunotherapy
CD227, CD229Cancer, immune modulation
CD252 (OX40L), CD254T-cell activation, cancer immunotherapy
CD257, CD267B-cell survival, autoimmune diseases
CD304Leukemia, lymphoma
CD305Cancer immunotherapy
CD309 (VEGFR2)Angiogenesis, cancer, vascular diseases
CD319Multiple myeloma, immune regulation
CD328, CD329NK cell pathways, cancer, immune modulation
CD335Natural killer (NK) cell biology
CD340 (HER2)Breast cancer, gastric cancer
IL-4, IL-21Cytokine biology, allergy, cancer immunotherapy
LRRC15Cancer stroma targeting
TNFα, TGFβR2Inflammatory diseases, cancer therapies

Applications Across
Therapy Areas

TruCytes are used across numerous therapy areas to enable innovation and reliability.

+ Applications

Immuno-oncology

CAR-T Cell Therapies

Hematology

Autoimmune Disease Research

Inflammatory Diseases

Allergy and Infectious Diseases

Cardiovascular

Central Nervous System

Metabolism and Obesity

Partner with Us

Slingshot Biosciences is your strategic partner offering a white-glove approach to customization, ensuring your TruCytes are optimized for your research goals. Whether you need a single protein, multiple distinct populations, or complex phenotypic markers, we deliver unparalleled quality and performance.

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